Morgan Gannon, who was a starting second-rower in last week’s loss to Hull FC, is ruled out because of concussion, but James Bentley has been named in Rhinos' initial squad for the first time this year.
James McDonnell, Liam Tindall, Sam Walters and Jack Sinfield are also included, along with the other 16 on duty in round two.
Here’s how Rhinos could line up as they bid for a first win against Saints in 13 Leeds meetings.
2. Wing: David Fusitua
Scored a try and had a solid game last week. Could switch to centre, with Liam Tindall at wing, but is probably better in his specialist role. Photo: Bruce Rollinson
3. Centre: Nene Macdonald
Had some good moments on debut last week and will be better for the hit out. Photo: Allan McKenzie/SWpix.com
4. Centre: Ash Handley
With Harry Newman still missing, Handley is likely to continue at left-centre. Photo: Alex Whitehead/SWpix.com
5. Wing: Derrell Olpherts
Winger Liam Tindall has been recalled to the initial 21, but Olpherts has more experience and will probably continue. Photo: Alex Whitehead/SWpix.com
6. Stand-off: Blake Austin
Hasn't made the best start to the campaign, but remains first-choice six. Photo: Bruce Rollinson